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Article

Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples.

Proceedings of the National Academy of Sciences of the United States of America - 16 Aug 2005

Liu Qing-Rong, Drgon Tomas, Walther Donna, Johnson Catherine, Poleskaya Oxanna, Hess Judith, Uhl George R

Abstract excerpt

Association genome scanning is of increasing interest for identifying the chromosomal regions that contain gene variants that contribute to vulnerability to complex disorders, including addictions. To improve the power and feasibility of this approach, we have validated "10k" microarray-based allelic frequency assessments in pooled DNA samples and have used this approach to seek allelic frequency differences...

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Identifiers

PMID: 16091475
DOI: 10.1073/pnas.0500329102
PMCID: PMC1183486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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