Article
Atypical Neocortical Development in the <i>Cited2</i> Conditional Knockout Leads to Behavioral Deficits Associated with Neurodevelopmental Disorders
2020-09-02
Abstract excerpt
The mammalian neocortex develops from a single layer of neuroepithelial cells to form a six-layer heterogeneous mosaic of differentiated neurons and glial cells. This process requires a complex choreography of temporally and spatially restricted transcription factors and epigenetic regulators. Even subtle disruptions in this regulation can alter the way the neocortex forms and functions, leading to a neurodevelopm...
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Identifiers and source
- Literature Corpus work
- 2796d60a-3ad9-5ada-82a6-000c2fa44538
- DOI
- 10.1101/2020.09.02.279646
