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Article

Aberrant MAD2 expression in soft‐tissue sarcoma

11 May 2008

Abstract excerpt

Soft-tissue sarcomas can be divided into translocation-associated (TA) and non-TA sarcomas, the latter of which is often characterized by pleomorphic cytomorphology and aneuploidy. The aberrant expression of MAD2, an essential component of the mitotic spindle checkpoint, has been recently shown to promote aneuploidy. The aim of the present paper was to assess MAD2 status on immunohistochemistry in 50 TA sarcomas...

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PMID: 18477210
DOI: 10.1111/j.1440-1827.2008.02232.x

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