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Article

Myxoid liposarcoma with nuclear pleomorphism: a clinicopathological and molecular study.

Virchows Archiv : an international journal of pathology - 1 Jan 2024

Kojima Naoki, Kubo Takashi, Mori Taisuke, Satomi Kaishi, Matsushita Yuko, Iwata Shintaro, Yatabe Yasushi, Ichimura Koichi, Kawai Akira, Ichikawa Hitoshi, Yoshida Akihiko

Abstract excerpt

Myxoid liposarcoma (MLS) is a common type of liposarcoma. It is characterized by variably lipogenic uniform cells in myxoid stroma with arborizing capillaries and DDIT3 fusion. Nuclear uniformity is the rule, which is maintained even in high-grade round cell examples. In this study, we conducted an in-depth investigation of four MLS tumors that demonstrated nuclear pleomorphism in three patients. These cases...

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PMID: 37704823
DOI: 10.1007/s00428-023-03631-5

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