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Article

Utility of fluorescence in situ hybridization to detect MDM2 amplification in liposarcomas and their morphological mimics.

International journal of clinical and experimental pathology - 1 Jan 2013

Kimura Hiroaki, Dobashi Yoh, Nojima Takayuki, Nakamura Hiroyuki, Yamamoto Norio, Tsuchiya Hiroyuki, Ikeda Hiroko, Sawada-Kitamura Seiko, Oyama Takeru, Ooi Akishi

Abstract excerpt

The atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS) and the de-differentiated liposarcoma (DDLS) represent the most common category of liposarcomas. ALT/WDLSs and DDLSs are often difficult to distinguish from other tumors with similar morphological characteristics. In this study, we investigated whether the detection of amplified or overexpressed murine double-minute 2 (MDM2) can be a...

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Identifiers

PMID: 23826411
PMCID: PMC3693195

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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