Article
Polymorphisms of the insertion / deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data.
BMC nephrology - 11 Jan 2005
Mondry Adrian, Loh Marie, Liu Pengbo, Zhu Ai-Ling, Nagel Mato
Abstract excerpt
BACKGROUND: Essential hypertension is a common, polygenic, complex disorder resulting from interaction of several genes with each other and with environmental factors such as obesity, dietary salt intake, and alcohol consumption. Since the underlying genetic pathways remain elusive, currently most studies focus on the genes coding for proteins that regulate blood pressure as their physiological role makes them...
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