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Article

Left ventricular diastolic function associated with common genetic variation in ATP12A in a general population.

BMC medical genetics - 4 Nov 2014

Knez Judita, Salvi Erika, Tikhonoff Valérie, Stolarz-Skrzypek Katarzyna, Ryabikov Andrew, Thijs Lutgarde, Braga Daniele, Kloch-Badelek Malgorzata, Malyutina Sofia, Casiglia Edoardo, Czarnecka Danuta, Kawecka-Jaszcz Kalina, Cusi Daniele, Nawrot Tim, Staessen Jan A, Kuznetsova Tatiana

Abstract excerpt

BACKGROUND: Left ventricular (LV) function depends on the activity of transmembrane electrolyte transporters. Failing human myocardium has lower Na(+)/K(+) ATPase expression and higher intracellular sodium concentrations. The ATP12A gene encodes a catalytic subunit of an ATPase that can function...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25366262
DOI: 10.1186/s12881-014-0121-6
PMCID: PMC4411923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25366262-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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