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Article

Taking multiple infections of cells and recombination into account leads to small within-host effective-population-size estimates of HIV-1.

PloS one - 13 Jan 2011

Balagam Rajesh, Singh Vasantika, Sagi Aparna Raju, Dixit Narendra M

Abstract excerpt

Whether HIV-1 evolution in infected individuals is dominated by deterministic or stochastic effects remains unclear because current estimates of the effective population size of HIV-1 in vivo, N(e), are widely varying. Models assuming HIV-1 evolution to be neutral estimate N(e)~10²-10⁴, smaller t...

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Identifiers

PMID: 21249189
DOI: 10.1371/journal.pone.0014531
PMCID: PMC3020941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21249189-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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