Article
The gene expression profiles of medulloblastoma cell lines resistant to preactivated cyclophosphamide.
Current cancer drug targets - 1 May 2008
Bacolod M D, Lin S M, Johnson S P, Bullock N S, Colvin M, Bigner D D, Friedman H S
Abstract excerpt
The total expression profiles of two medulloblastoma cell lines resistant to the preactivated form of cyclophosphamide (4-hydroperoxycyclophosphamide, 4-HC) were examined using the Affymetrix GeneChip U133A array. Our primary objective was to look for possible genes, other than the well-studied aldehyde dehydrogenases (ALDH) that may be involved in cyclophosphamide (CP) resistance in medulloblastomas. We present...
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