Article
Chromosomal imbalances associated with drug resistance and thermoresistance in human pancreatic carcinoma cells.
European journal of cell biology - 1 Oct 2004
Tönnies Holger, Lage Hermann
Abstract excerpt
Resistance to therapeutic treatment is the major obstacle to advances in the successful management of pancreatic cancer. To characterize chromosomal alterations associated with different phenotypes of acquired multidrug resistance (MDR) and thermoresistance, comparative genomic hybridization (CGH) was applied to compare human pancreatic carcinoma-derived cells. This panel of cell lines consists of the parental,...
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