Article
Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis.
Arthritis research & therapy - 1 Jan 2008
Shi Dongquan, Nakamura Takahiro, Nakajima Masahiro, Dai Jin, Qin Jianghui, Ni Haijian, Xu Yong, Yao Chen, Wei Jia, Liu Baorui, Ikegawa Shiro, Jiang Qing
Abstract excerpt
INTRODUCTION: Conflicting findings on the association of single nucleotide polymorphisms (SNPs) in RHOB and TXNDC3 with susceptibility to knee osteoarthritis (OA) have been reported in European Caucasians. To examine the associations of these SNPs with OA in East Asian populations and to evaluate their global significance, we conducted two case-control studies in 955 Chinese and 750 Japanese patients. METHODS: We...
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