Article
Nucleotide sequence of a variant protein A of Staphylococcus aureus suggests molecular heterogeneity among strains.
Journal of basic microbiology - 1 Jan 1991
Brígido M de M, Barardi C R, Bonjardin C A, Santos C L, Junqueira M L, Brentani R R
Abstract excerpt
Protein A is a cell wall linked protein of Staphylococcus aureus that binds mammalian IgG. Although protein A displays high size heterogeneity among strains, cloning and sequencing of its gene from two strains had not shown a large difference in size. Here we report a third protein A gene sequence that shows a size variation relative to these two, due to deletions on both one IgG binding domain and a cell wall...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Biological Evolution
- Cloning, Molecular
- Genetic Variation
- Immunoglobulin G
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Sequence Homology, Nucleic Acid