Article
Challenges for the evaluation of Staphylococcus aureus protein based vaccines: monitoring antigenic diversity.
Human vaccines - 1 Jan 2000
Murphy Ellen, Lin Shuo L, Nunez Lorna, Andrew Lubomira, Fink Pamela S, Dilts Deborah A, Hoiseth Susan K, Jansen Kathrin U, Anderson Annaliesa S
Abstract excerpt
Clumping factors A (ClfA) and B (ClfB) are Staphylococcus aureus virulence proteins that are displayed on the cell surface of the organism and have potential as vaccine antigens for the prevention of S. aureus disease. Here we evaluate the phylogeny of S. aureus in the context of antigenic variat...
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