Article
Integrative computational approach to evaluate risk genes for postmenopausal osteoporosis.
IET systems biology - 1 Jun 2018
Sheng Yingjun, Tang Jilei, Ren Kewei, Manor Lydia C, Cao Hongbao
Abstract excerpt
In recent years, numerous studies reported over a hundred of genes playing roles in the etiology of postmenopausal osteoporosis (PO). However, many of these candidate genes were lack of replication and results were not always consistent. Here, the authors proposed a computational workflow to curate and evaluate PO related genes. They integrate large-scale literature knowledge data and gene expression data (PO...
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