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Article

Reconstitution models to evaluate natural killer T cell function in tumor control.

Immunology and cell biology - 1 Jan 2016

Gebremeskel Simon, Slauenwhite Drew, Johnston Brent

Abstract excerpt

Natural killer T (NKT) cells are glycolipid-reactive T lymphocytes that function in immunosurveillance and immune regulation. However, reduced tumor control in NKT cell-deficient Jα18(-/-) mice may be confounded by an overall reduction in T-cell receptor (TCR) repertoire diversity in these animals. Mechanistic studies are also hindered by a lack of tools to target molecules specifically in NKT cells. To address...

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Identifiers

PMID: 26095148
DOI: 10.1038/icb.2015.67

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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