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Article

Transcription factor PU.1 is expressed in white adipose and inhibits adipocyte differentiation

8 May 2008

Abstract excerpt

PU.1 transcription factor is a critical regulator of hematopoiesis and leukemogenesis. Because PU.1 interacts with transcription factors GATA-2 and C/EBPalpha, and both are involved in the regulation of adipogenesis, we investigated whether PU.1 plays a role in the regulation of adipocyte differentiation. Our data indicate that PU.1 is expressed in white adipose tissue. PU.1 protein can also be detected in...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 18463231
DOI: 10.1152/ajpcell.00422.2007

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