Article
Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload.
Journal of hepatology - 1 Jul 2008
Barisani Donatella, Pelucchi Sara, Mariani Raffaella, Galimberti Stefania, Trombini Paola, Fumagalli Daniela, Meneveri Raffaella, Nemeth Elizabeta, Ganz Tomas, Piperno Alberto
Abstract excerpt
BACKGROUND/AIMS: Many patients with hepatic iron overload do not have identifiable mutations and often present with metabolic disorders and hepatic steatosis. Since the pathophysiology of Dysmetabolic Hepatic Iron Overload (DHIO) is still obscure, the aim of this study was to evaluate, in these patients, possible alterations in iron-related molecule expression. METHODS: Iron-related gene mRNA levels were...
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