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Article

Relationship between gene expression of duodenal iron transporters and iron stores in hemochromatosis subjects.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jan 2010

Nelson James E, Mugford Virginia R, Kilcourse Ellen, Wang Richard S, Kowdley Kris V

Abstract excerpt

To test the hypothesis that differences in duodenal iron absorption may explain the variable phenotypic expression among HFE C282Y homozygotes, we have compared relative gene expression of duodenal iron transporters among C282Y homozygotes [hereditary hemochromatosis (HH)] with and without iron overload. Duodenal biopsy samples were analyzed using real-time PCR for expression of DMT1, FPN1, DCYTB, and HEPH...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19892936
DOI: 10.1152/ajpgi.00175.2009
PMCID: PMC2806103

Genes

HEPH
HFE
GAPDH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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