Article
The leucine-rich repeat domain of Internalin B folds along a polarized N-terminal pathway.
Structure (London, England : 1993) - 1 May 2008
Courtemanche Naomi, Barrick Doug
Abstract excerpt
The leucine-rich repeat domain of Internalin B is composed of seven tandem leucine-rich repeats, which each contain a short beta strand connected to a 3(10) helix by a short turn, and an N-terminal alpha-helical capping motif. To determine whether folding proceeds along a single, discrete pathway or multiple, parallel pathways, and to map the structure of the transition state ensemble, we examined the effects of...
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