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Article

Retinoic acid promotes density-dependent growth arrest in human retinal pigment epithelial cells.

Investigative ophthalmology & visual science - 1 Jan 1991

Campochiaro P A, Hackett S F, Conway B P

Abstract excerpt

After retinal detachment the retinal pigment epithelium (RPE) undergoes a striking phenotypic change. It becomes dedifferentiated, proliferates to form multilayered colonies, and migrates into the subretinal space. These processes are important because they have been implicated in proliferative vitreoretinopathy and poor visual recovery after retinal reattachment; however the mechanisms by which they occur are...

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Source

Identifiers

PMID: 1846132

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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