Additional sequence complexity in the muscle gene, unc-22, and its encoded protein, twitchin, of Caenorhabditis elegans.

doi:10.1093/genetics/134.4.1097

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Additional sequence complexity in the muscle gene, unc-22, and its encoded protein, twitchin, of Caenorhabditis elegans.

Genetics - 1 Aug 1993

Benian G M, L'Hernault S W, Morris M E

Abstract excerpt

Null mutations of the Caenorhabditis elegans unc-22 gene cause a pronounced body surface twitch associated with impaired movement and disruption of muscle structure. Partial sequence analysis of unc-22 has previously revealed that its encoded polypeptide, named twitchin, consists of a single prot...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Blotting, Western
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Calmodulin-Binding Proteins
DNA
DNA Transposable Elements
Helminth Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle Proteins

Muscles

Phenotype

Polymerase Chain Reaction

RNA Splicing

Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 8397135
DOI: 10.1093/genetics/134.4.1097
PMCID: PMC1205578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8397135-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Additional sequence complexity in the muscle gene, unc-22, and its encoded protein, twitchin, of Caenorhabditis elegans.PMID 8397135Read ↗

Mutations in the unc-52 gene responsible for body wall muscle defects in adult Caenorhabditis elegans are located in alternatively spliced exons.Semantic proximity Read ↗

Twitchin kinase inhibits muscle activity.Semantic proximity Read ↗

The Caenorhabditis elegans muscle-affecting gene unc-87 encodes a novel thin filament-associated protein.Semantic proximity Read ↗

The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein.Semantic proximity Read ↗

The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction.Semantic proximity Read ↗

Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33.Semantic proximity Read ↗

Developmental genetic analysis of troponin T mutations in striated and nonstriated muscle cells of Caenorhabditis elegans.Semantic proximity Read ↗

Molecular cloning and characterization of the dpy-20 gene of Caenorhabditis elegans.Semantic proximity Read ↗

Analysis of smu-1, a gene that regulates the alternative splicing of unc-52 pre-mRNA in Caenorhabditis elegans.Semantic proximity Read ↗

Mutations in the sup-38 gene of Caenorhabditis elegans suppress muscle-attachment defects in unc-52 mutants.Semantic proximity Read ↗

unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction.Semantic proximity Read ↗

Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.