Article
The Caenorhabditis elegans muscle-affecting gene unc-87 encodes a novel thin filament-associated protein.
The Journal of cell biology - 1 Oct 1994
Goetinck S, Waterston R H
Abstract excerpt
Mutations in the unc-87 gene of Caenorhabditis elegans affect the structure and function of bodywall muscle, resulting in variable paralysis. We cloned the unc-87 gene by taking advantage of a transposon-induced allele of unc-87 and the correspondence of the genetic and physical maps in C. elegans. A genomic clone was isolated that alleviates the mutant phenotype when introduced into unc-87 mutants. Sequence...
Topics
- Actin Cytoskeleton
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Antibodies, Helminth
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cloning, Molecular
- DNA, Complementary
- DNA, Helminth