Article
Mutations in the quinolone resistance determining region in Staphylococcus epidermidis recovered from conjunctiva and their association with susceptibility to various fluoroquinolones.
The British journal of ophthalmology - 1 Jun 2008
Yamada M, Yoshida J, Hatou S, Yoshida T, Minagawa Y
Abstract excerpt
BACKGROUND: Staphylococcus epidermidis is one of the prominent pathogens in ocular infection. The prevalence of mutations in the quinolone resistance determining region (QRDR) area in S epidermidis isolated from the ocular surface and its association with fluoroquinolone resistance has not been f...
Topics
- Aza Compounds
- Conjunctiva
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Multiple, Bacterial
- Fluoroquinolones
- Gatifloxacin
- Genes, MDR
- Humans
- Levofloxacin
- Microbial Sensitivity Tests
- Moxifloxacin
- Mutation
- Naphthyridines
- Ofloxacin