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Article

Rapid detection of fluoroquinolone-resistant Staphylococcus epidermidis and its associated mutations in the quinolone resistance-determining region.

Experimental eye research - 1 Jun 2026

Kato Nobuhiro, Haruta Masatoshi, Arai Rikki, Sato Kazunori, Furushima Kei, Okuno Miki, Yamamoto Takeshi, Ogura Yoshitoshi, Yoshida Shigeo

Abstract excerpt

The purpose of this study was to investigate the relationship between amino acid mutations in the quinolone resistance-determining region (QRDR) of Staphylococcus epidermidis and its susceptibility to fluoroquinolones, as well as the potential of single nucleotide polymorphism (SNP) genotyping for rapid detection of resistant strains. Thirty-three S. epidermidis strains were analyzed (25 from preoperative...

Topics

Staphylococcus epidermidis
Fluoroquinolones
Microbial Sensitivity Tests
Humans
Anti-Bacterial Agents
Polymorphism, Single Nucleotide
Drug Resistance, Bacterial
Mutation
DNA Gyrase
DNA Topoisomerase IV

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Staphylococcal Infections

DNA, Bacterial

Genotype

Eye Infections, Bacterial

Source

Identifiers

PMID: 41839383
DOI: 10.1016/j.exer.2026.110973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41839383-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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