Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of QRDR mutations and MIC levels in fluoroquinolone-resistant Staphylococcus aureus clinical isolates.

Microbiology spectrum - 4 Nov 2025

Kim Sohyeong, Xuan Xianglan, Jung Minju, Park Yujin, Kim Soyun, Woo Gaeun, Park Heechul, Kim Sangha, Lee Jiyoung, Park Min, Kim Sunghyun

Abstract excerpt

Antimicrobial resistance is a global health problem. Among various antibiotic-resistant bacteria, Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA), is a clinically important pathogen responsible for serious infections because of its multidrug resistance (MDR) and associa...

Topics

Microbial Sensitivity Tests
Humans
Anti-Bacterial Agents
Fluoroquinolones
Staphylococcal Infections
Staphylococcus aureus
Mutation
Drug Resistance, Bacterial
DNA Topoisomerase IV
DNA Gyrase
Drug Resistance, Multiple, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ciprofloxacin

Bacterial Proteins

Methicillin-Resistant Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 41081515
DOI: 10.1128/spectrum.00645-25
PMCID: PMC12584750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-41081515-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of QRDR mutations and MIC levels in fluoroquinolone-resistant Staphylococcus aureus clinical isolates.PMID 41081515Read ↗

Emerging strategies and therapeutic innovations for combating drug resistance in Staphylococcus aureus strains: A comprehensive reviewSemantic proximity Read ↗

Genomic Epidemiology and Emerging Mechanisms of Antibiotic Resistance Among Clinically Significant BacteriaSemantic proximity Read ↗

Rapid detection of fluoroquinolone-resistant Staphylococcus epidermidis and its associated mutations in the quinolone resistance-determining region.Semantic proximity Read ↗

Phenotypic and genotypic evaluation of fluoroquinolone resistance in clinical isolates of Staphylococcus aureus in Tehran.Semantic proximity Read ↗

Analyzing genomic alterations involved in fluoroquinolone-resistant development in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Antimicrobial resistance in methicillin-resistant staphylococcus aureusSemantic proximity Read ↗

Impact of co-existence of PMQR genes and QRDR mutations on fluoroquinolones resistance in Enterobacteriaceae strains isolated from community and hospital acquired UTIs.Semantic proximity Read ↗

Genetics of antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA)Semantic proximity Read ↗

The role of Gene Mutations (gyrA, parC) in Resistance to Ciprofloxacin in Clinical Isolates of Pseudomonas AeruginosaSemantic proximity Read ↗

Molecular diagnostics for genotypic detection of antibiotic resistance: current landscape and future directionsSemantic proximity Read ↗

Whole Genome Sequenced-based Characterization and Determination of quinolone Resistance Among Methicillin-resistant and Methicillin-susceptible S. aureus isolates from Patients Attended Regional Referral Hospitals in TanzaniaSemantic proximity Read ↗

An approach to identifying drug resistance associated mutations in bacterial strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.