Article
Changes in drug susceptibility and the quinolone-resistance determining region of Staphylococcus epidermidis after administration of fluoroquinolones.
Journal of cataract and refractive surgery - 1 Nov 2009
Miyanaga Masaru, Nejima Ryohei, Miyai Takashi, Miyata Kazunori, Ohashi Yuichi, Inoue Yoshitsugu, Toyokawa Masahiro, Asari Seishi
Abstract excerpt
PURPOSE: To evaluate the correlation between changes in the susceptibility of bacteria and mutations in the quinolone-resistance determining region (QRDR) after 3 weeks of continuous fluoroquinolone instillation. SETTING: Miyata Eye Hospital, Miyazaki, Japan. METHODS: In this prospective randomized study, gatifloxacin 0.3% eyedrops or levofloxacin 0.5% eyedrops were administered for 1 week before cataract surgery...
Topics
- Aged
- Aged, 80 and over
- Bacterial Proteins
- Cataract Extraction
- Conjunctiva
- Drug Resistance, Multiple, Bacterial
- Fluoroquinolones
- Gatifloxacin
- Genes, MDR
- Humans
- Levofloxacin
- Microbial Sensitivity Tests
- Mutation