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Article

Malignant melanoma in patients with hereditary nonpolyposis colorectal cancer.

The British journal of dermatology - 1 Jul 2008

Ponti G, Losi L, Pellacani G, Wannesson L, Cesinaro A M, Venesio T, Petti C, Seidenari S

Abstract excerpt

BACKGROUND: Malignant melanoma (MM) is the most aggressive skin cancer. Most MMs are sporadic, and in this setting an association with mismatch repair (MMR) gene mutations, typical of hereditary nonpolyposis colorectal cancer (HNPCC) tumours, has been proposed. OBJECTIVES: To characterize clinically and/or by molecular biology the patients with MM belonging to a cohort of 60 kindreds with HNPCC. Methods Patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18460031
DOI: 10.1111/j.1365-2133.2008.08575.x

Genes

MSH2
BRAF
MLH1
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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