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Article

GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48.

Molecular and cellular biology - 1 Jul 2008

Caruso Marie-Elaine, Jenna Sarah, Bouchecareilh Marion, Baillie David L, Boismenu Daniel, Halawani Dalia, Latterich Martin, Chevet Eric

Abstract excerpt

When endoplasmic reticulum (ER) homeostasis is perturbed, an adaptive mechanism is triggered and named the unfolded protein response (UPR). Thus far, three known UPR signaling branches (IRE-1, PERK, and ATF-6) mediate the reestablishment of ER functions but can also lead to apoptosis if ER stress...

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PMID: 18458060
DOI: 10.1128/MCB.02252-07
PMCID: PMC2447140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18458060-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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