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Article

Family-based association of a low producing lymphotoxin-alpha allele with reduced Plasmodium falciparum parasitemia.

Microbes and infection - 1 May 2008

Barbier Mathieu, Delahaye Nicolas F, Fumoux Francis, Rihet Pascal

Abstract excerpt

Tumor necrosis factor (TNF)-related genes are thought to play a role in human malaria. TNF polymorphisms have been associated with severe malaria, mild malaria, and parasitemia. Lymphotoxin-alpha gene (LTA) that belongs to the TNF family is one such candidate gene. Here we report the family-based association analysis of a cis-regulatory lymphotoxin-alpha polymorphism with parasitemia in two independent...

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Source

Identifiers

PMID: 18457972
DOI: 10.1016/j.micinf.2008.03.001

Genes

LTA
TNF

Provenance

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