Article
Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China.
Journal of toxicology and environmental health. Part A - 1 Jan 2010
Liu Ran, Yin Lihong, Pu Yuepu, Li Yunhui, Liang Geyu, Zhang Juan, Li Xiaobo
Abstract excerpt
Glutathione S-transferases (GST) belong to a superfamily of phase II enzymes believed to be associated with enhanced frequency of esophageal carcinoma. This study was performed to evaluate whether the GST family was associated with susceptibility to esophageal carcinoma in China. Ninety-seven patients with newly diagnosed, untreated esophageal squamous-cell carcinoma (ESCC) and 97 healthy controls matched in age,...
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