Article
Genetic polymorphism of p53, but not GSTP1, is association with susceptibility to esophageal cancer risk - a meta-analysis.
International journal of medical sciences - 1 Sept 2010
Zhao Yaping, Wang Furu, Shan Shunlin, Zhao Yiqi, Qiu Xueming, Li Xiangyang, Jiao Feng, Wang Jianguo, Du Yunxiang
Abstract excerpt
A number of studies have evaluated two functional polymorphisms on p53 Arg72Pro and GSTP1 Ile105Val, in relation to esophageal cancer susceptibility. However, the results remain conflicting rather than conclusive. This meta-analysis on 2919 cases and 4074 controls for p53 Arg72Pro and 1885 cases and 2194 controls for GSTP1 Ile105Val from 13 published case-control studies showed that no significant general main...
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