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Article

Interactions between Glutathione-S-Transferase M1, T1 and P1 polymorphisms and smoking, and increased susceptibility to esophageal squamous cell carcinoma.

Cancer epidemiology - 1 Jun 2010

Moaven Omeed, Raziee Hamid Reza, Sima Hamid Reza, Ganji Azita, Malekzadeh Reza, A'rabi Azadeh, Abdollahi Abbas, Memar Bahram, Sotoudeh Masoud, Naseh Hossein, Nekoui Navid, Razavipour Adeleh, Gholamin Mehran, Dadkhah Ezzat, Farshchian Moein, Abbaszadegan Mohammad Reza

Abstract excerpt

BACKGROUND: A complex of genetic and environmental factors is involved in carcinogenesis of the esophageal squamous cell carcinoma (ESCC). Glutathione-S-Transferases (GSTs) are phase-II enzymes playing role in detoxification of carcinogen electrophiles. Genetic polymorphisms of GSTM1, GSTT1 and G...

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Source

Identifiers

PMID: 20409775
DOI: 10.1016/j.canep.2010.03.009

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20409775-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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