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Article

Multiple genotypic aberrances associate to terminal differentiation-deficiency of an oral squamous cell carcinoma in serum-free culture.

Differentiation; research in biological diversity - 1 Oct 2008

Roberg Karin, Ceder Rebecca, Farnebo Lovisa, Norberg-Spaak Lena, Grafström Roland C

Abstract excerpt

Oral squamous cell carcinoma (OSCC) lines proliferative in the serum-free conditions devised for normal oral keratinocytes (NOK) are virtually absent, complicating studies of carcinogenesis. A tongue squamous cell carcinoma generated under conditions for normal cell culture an apparently immortal line (termed LK0412) that has undergone >or=200 population doublings from over a year in culture. LK0412 exhibited...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18452551
DOI: 10.1111/j.1432-0436.2008.00267.x

Genes

BAX
BST2
CRIP1
ISG15
KLRC1
NEDD9
NNMT
TWIST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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