Article
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.
Immunity - 1 May 2008
Teng Grace, Hakimpour Paul, Landgraf Pablo, Rice Amanda, Tuschl Thomas, Casellas Rafael, Papavasiliou F Nina
Abstract excerpt
B lymphocytes perform somatic hypermutation and class-switch recombination (CSR) of the immunoglobulin locus to generate an antibody repertoire diverse in both affinity and function. These somatic diversification processes are catalyzed by activation-induced cytidine deaminase (AID), a potent DNA...
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