Article
Validating endophenotypes for schizophrenia using statistical modeling of twin data.
Clinical EEG and neuroscience - 1 Apr 2008
Hall Mei-Hua, Rijsdijk Früling
Abstract excerpt
The use of endophenotypes (intermediate quantitative traits) is one strategy that may provide valuable information about the neural mechanisms underlying disease etiology and facilitate discovery of susceptibility genes. For a trait to be an appropriate endophenotype, several key features should exist. In this article we discuss validating potential electrophysiological endophenotypes for schizophrenia based on...
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