Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures.

doi:10.1093/schbul/sbl060

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Article

Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures.

Schizophrenia bulletin - 1 Jan 2007

Turetsky Bruce I, Calkins Monica E, Light Gregory A, Olincy Ann, Radant Allen D, Swerdlow Neal R

Abstract excerpt

In an effort to reveal susceptibility genes, schizophrenia research has turned to the endophenotype strategy. Endophenotypes are characteristics that reflect the actions of genes predisposing an individual to a disorder, even in the absence of diagnosable pathology. Individual endophenotypes are presumably determined by fewer genes than the more complex phenotype of schizophrenia and would, therefore, reduce the...

Topics

Arousal
Attention
Brain
Contingent Negative Variation
Discrimination Learning
Event-Related Potentials, P300
Evoked Potentials, Auditory
Genetic Predisposition to Disease
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neural Inhibition

Phenotype

Reflex, Startle

Saccades

Schizophrenia

Twin Studies as Topic

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Identifiers

PMID: 17135482
DOI: 10.1093/schbul/sbl060
PMCID: PMC2632291

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