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Article

Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures.

Schizophrenia bulletin - 1 Jan 2007

Turetsky Bruce I, Calkins Monica E, Light Gregory A, Olincy Ann, Radant Allen D, Swerdlow Neal R

Abstract excerpt

In an effort to reveal susceptibility genes, schizophrenia research has turned to the endophenotype strategy. Endophenotypes are characteristics that reflect the actions of genes predisposing an individual to a disorder, even in the absence of diagnosable pathology. Individual endophenotypes are presumably determined by fewer genes than the more complex phenotype of schizophrenia and would, therefore, reduce the...

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Identifiers

PMID: 17135482
DOI: 10.1093/schbul/sbl060
PMCID: PMC2632291

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