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Article

Characterization of the genotoxicity of nitrilotriacetic acid.

Environmental and molecular mutagenesis - 1 Jul 2008

Nesslany Fabrice, Simar-Meintières Sophie, Watzinger Malene, Talahari Ismail, Marzin Daniel

Abstract excerpt

The chelating agent nitrilotriacetic acid (NTA), classified as an epigenetic rodent carcinogen, was assessed in the in vivo rodent Comet assay on isolated kidney cells. Unexpected potent increases in DNA damage were obtained in both the short (3-6 hr) and long-term (22-26 hr) expression times after a single oral treatment at 1,000-2,000 mg/kg bw. NTA was assayed in the Ames test using TA1537, TA98, TA100, and...

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PMID: 18449932
DOI: 10.1002/em.20403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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