Characterization of the genotoxicity of nitrilotriacetic acid.

doi:10.1002/em.20403

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Article

Characterization of the genotoxicity of nitrilotriacetic acid.

Environmental and molecular mutagenesis - 1 Jul 2008

Nesslany Fabrice, Simar-Meintières Sophie, Watzinger Malene, Talahari Ismail, Marzin Daniel

Abstract excerpt

The chelating agent nitrilotriacetic acid (NTA), classified as an epigenetic rodent carcinogen, was assessed in the in vivo rodent Comet assay on isolated kidney cells. Unexpected potent increases in DNA damage were obtained in both the short (3-6 hr) and long-term (22-26 hr) expression times aft...

Topics

Adult
Animals
Apoptosis
Cell Line, Tumor
Cells, Cultured
Chlorodiphenyl (54% Chlorine)
Chromosome Aberrations
Comet Assay
DNA Damage
Humans
Kidney
Liver
Lymphocytes
Male
Mice
Mice, Inbred C57BL
Micronucleus Tests
Mitotic Index

Source

Open in PubMed

Identifiers

PMID: 18449932
DOI: 10.1002/em.20403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-18449932-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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