Cytotoxicity and mutagenicity of 2,4,6-trinitrotoluene and its metabolites.

doi:10.1006/eesa.1996.0112

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Article

Cytotoxicity and mutagenicity of 2,4,6-trinitrotoluene and its metabolites.

Ecotoxicology and environmental safety - 1 Dec 1996

Honeycutt M E, Jarvis A S, McFarland V A

Abstract excerpt

Composting has been advocated and is being used as an economical method for remediating 2,4,6-trinitrotoluene (TNT)-contaminated soils. However, evidence suggests that TNT is transformed into products of unknown toxicity during the process. This study was undertaken to examine the in vitro cytoto...

Topics

Animals
Biotransformation
CHO Cells
Cricetinae
Cricetulus
Lethal Dose 50
Mutagenicity Tests
Mutation
Soil Pollutants
Structure-Activity Relationship
Trinitrotoluene

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