Article
Genetics of Asthma and Allergic Diseases.
Handbook of experimental pharmacology - 1 Jan 2022
Haider Sadia, Simpson Angela, Custovic Adnan
Abstract excerpt
Asthma genes have been identified through a range of approaches, from candidate gene association studies and family-based genome-wide linkage analyses to genome-wide association studies (GWAS). The first GWAS of asthma, reported in 2007, identified multiple markers on chromosome 17q21 as associates of the childhood-onset asthma. This remains the best replicated asthma locus to date. However, notwithstanding...
Topics
- Asthma
- Child
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Hypersensitivity