Article
<i>Helicobacter pylori</i>Outer Membrane Protein 18 (Hp1125) Is Involved in Persistent Colonization by Evading Interferon-<i>γ</i>Signaling
1 Jan 2015
Abstract excerpt
Outer membrane proteins (OMPs) can induce an immune response. Omp18 (HP1125) of H. pylori is a powerful antigen that can induce significant interferon-γ (IFN-γ) levels. Previous studies have suggested that IFN-γ plays an important role in H. pylori clearance. However, H. pylori has multiple mechanisms to avoid host immune surveillance for persistent colonization. We generated an omp18 mutant (H. pylori 26695 and...
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