Article

Regulation of auditory fear discrimination by the novel Kv3 voltage-gated potassium channel modulator AUT00206

2021-06-15

Abstract excerpt

Psychiatric diseases like anxiety-related disorders and schizophrenia are characterized by impaired cognition and emotional regulation linked to corticolimbic disinhibition. Restoring the balance between excitation and inhibition in corticolimbic circuits may therefore ameliorate certain features of these disorders, such as inappropriately attributing affective salience to innocuous cues. Corticolimbic activity is...

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Literature Corpus work: d7fc67da-671c-5dea-b844-e296b6bf2d7a
DOI: 10.1101/2021.06.15.448180

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