Association of interferon regulatory factor 5 haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis.

doi:10.1002/art.23426

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Article

Association of interferon regulatory factor 5 haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis.

Arthritis and rheumatism - 1 May 2008

Dieguez-Gonzalez Rebeca, Calaza Manuel, Perez-Pampin Eva, de la Serna Arturo Rodriguez, Fernandez-Gutierrez Benjamin, Castañeda Santos, Largo Raquel, Joven Beatriz, Narvaez Javier, Navarro Federico, Marenco Jose Luis, Vicario Jose Luis, Blanco Francisco J, Fernandez-Lopez Jesus Carlos, Caliz Rafael, Collado-Escobar María Dolores, Carreño Luis, Lopez-Longo Javier, Cañete Juan D, Gomez-Reino Juan J, Gonzalez Antonio

Abstract excerpt

OBJECTIVE: Previous studies have shown either a lack of effect of IRF5 polymorphisms or an association of the IRF5 gene in only a minor subset of rheumatoid arthritis (RA) patients in whom anti-citrullinated protein antibodies (ACPAs) are absent. The present study was undertaken to investigate the role of genetic variation in IRF5 in susceptibility to RA. METHODS: Nine IRF5 single-nucleotide polymorphisms (SNPs)...

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PMID: 18438842
DOI: 10.1002/art.23426

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PTPN22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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