Article
Preferential association of interferon regulatory factor 5 gene variants with seronegative rheumatoid arthritis in 2 Swedish case-control studies.
The Journal of rheumatology - 1 Oct 2011
Wang Chuan, Kokkonen Heidi, Sandling Johanna K, Johansson Martin, Seddighzadeh Maria, Padyukov Leonid, Rantapää-Dahlqvist Solbritt, Syvänen Ann-Christine
Abstract excerpt
OBJECTIVE: Two interferon regulatory factor 5 (IRF5) gene variants were examined for association with rheumatoid arthritis (RA). METHODS: A total of 2300 patients with RA and 1836 controls were recruited from 2 independent RA studies in Sweden. One insertion-deletion polymorphism (CGGGG indel) and one single-nucleotide polymorphism (rs10488631) in the IRF5 gene were genotyped and analyzed within RA subgroups...
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