Article
Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 2003
Chang Alfred E, Li Qiao, Jiang Guihua, Sayre Donna M, Braun Thomas M, Redman Bruce G
Abstract excerpt
PURPOSE: Previous preclinical and clinical studies have demonstrated that autologous tumor vaccines can induce relatively specific tumor-reactive T cells in draining lymph nodes. The adoptive transfer of these cells can result in tumor regression. PATIENTS AND METHODS: Patients with stage IV renal cell cancer (RCC) were vaccinated with irradiated autologous tumor cells admixed with Calmette-Guérin bacillus....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
