Article
Multidrug resistance in patients undergoing resective epilepsy surgery is not associated with C3435T polymorphism in the ABCB1 (MDR1) gene.
Epilepsy research - 1 Jul 2008
Dericioglu Nese, Babaoglu Melih O, Yasar Umit, Bal I Burak, Bozkurt Atila, Saygi Serap
Abstract excerpt
PURPOSE: The C3435T polymorphism in the gene coding for P-glycoprotein (ABCB1) has been correlated with drug resistance in patients with epilepsy. However, replication studies have revealed conflicting results and the reason for this is not clear. We investigated the frequency of C3435T polymorphism in epileptic Turkish patients who underwent resective epilepsy surgery and compared our results with healthy...
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