Article
Polymorphisms in the receptor for GDNF (RET) are not associated with Parkinson's disease in Southern Germany.
Neurobiology of aging - 1 Jan 2010
Lücking C B, Lichtner P, Kramer E R, Gieger C, Illig T, Dichgans M, Berg D, Gasser T
Abstract excerpt
The aetiology of the selective neurodegeneration in Parkinson's disease (PD) is still unknown. Neurotrophic factors, e.g. glial cell line-derived neurotrophic factor (GDNF), have been shown to promote survival of dopaminergic neurons. Interestingly, aged mice lacking GDNF-receptor (RET) in their...
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