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Article

Interaction between the dopamine D4 receptor and the serotonin transporter promoter polymorphisms in alcohol and tobacco use among 15-year-olds.

Neurogenetics - 1 Nov 2006

Skowronek M H, Laucht M, Hohm E, Becker K, Schmidt M H

Abstract excerpt

Early onset of alcohol and tobacco use during adolescence increases the risk for establishing a substance use disorder in adulthood. Both alcohol and nicotine stimulate the dopamine (DA) and the serotonin (5-HT) systems. The DA system has been implicated in the mediation of the rewarding effects...

Read the complete abstract on PubMed

Topics

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Share to Adolescent
Share to Alcoholism
Share to Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Receptors, Dopamine D4

Share to Risk Factors

Share to Serotonin Plasma Membrane Transport Proteins

Share to Smoking

Source

Identifiers

PMID: 16819620
DOI: 10.1007/s10048-006-0050-4

Genes

DRD4
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16819620-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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