Article
Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians.
Osteoarthritis and cartilage - 1 Oct 2008
Atif U, Philip A, Aponte J, Woldu E M, Brady S, Kraus V B, Jordan J M, Doherty M, Wilson A G, Moskowitz R W, Hochberg M, Loeser R, Renner J B, Chiano M
Abstract excerpt
OBJECTIVE: An association between osteoarthritis (OA) and functional polymorphisms in the aspartic acid (d) repeat of the asporin (ASPN) gene was reported in Japanese and Han Chinese populations. The aim of this study was to assess the association of variants in the ASPN gene with the presence of radiographic hand and/or knee OA in a US Caucasian population. METHODS: Ten single nucleotide polymorphisms (SNPs)...
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