Article
Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis.
Osteoarthritis and cartilage - 1 Nov 2013
Xing D, Ma X-L, Ma J-X, Xu W-G, Wang J, Yang Y, Chen Y, Ma B-Y, Zhu S-W
Abstract excerpt
OBJECTIVE: Knee osteoarthritis (KOA) is a common disease that is characterized by the degeneration of joint cartilage in the knee. Genetic factors have been implicated in KOA. Recently, several genetic studies have suggested that susceptibility to KOA is affected by the number of aspartic acid (D) residues in the amino-terminal of the asporin protein, but evidence remains conflicting. Therefore, the objective of...
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