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Article

High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.

Journal of human genetics - 1 Jan 2006

Iida Aritoshi, Kizawa Hideki, Nakamura Yusuke, Ikegawa Shiro

Abstract excerpt

Osteoarthritis (OA) is a very common bone and joint disease characterized by breakdown of cartilage in the joint. We recently found that an aspartic-acid repeat polymorphism of the asporin gene (ASPN) on chromosome 9 is associated with susceptibility to OA in Japanese. We provide here a high-resolution single nucleotide polymorphism (SNP) map within a 33.4-kb genomic region containing ASPN. A total of 19 SNPs...

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Identifiers

PMID: 16311710
DOI: 10.1007/s10038-005-0337-6

Genes

ASPN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.PMID 16311710Read ↗

[Asporin, a susceptibility gene for osteoarthritis].Semantic proximity Read ↗

A meta-analysis of the relationship between aspartic acid (D)-repeat polymorphisms in asporin and osteoarthritis susceptibility.Semantic proximity Read ↗

Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population.Semantic proximity Read ↗

Association of the aspartic acid-repeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population.Semantic proximity Read ↗

Association between single nucleotide polymorphisms of asporin (ASPN) and BMP5 with the risk of knee osteoarthritis in a Chinese Han population.Semantic proximity Read ↗

Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians.Semantic proximity Read ↗

Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese.Semantic proximity Read ↗

Meta-analysis of association between the ASPN D-repeat and osteoarthritis.Semantic proximity Read ↗

Investigation of the asporin gene polymorphism as a risk factor for knee osteoarthritis in Iran.Semantic proximity Read ↗

Association between aspartic acid repeat polymorphism of the asporin gene and susceptibility to knee osteoarthritis: a genetic meta-analysis.Semantic proximity Read ↗

Association of the asporin D14 allele with lumbar-disc degeneration in Asians.Semantic proximity Read ↗

Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians.Semantic proximity Read ↗

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